Juventus vs. Atalanta (Wednesday, 5.30pm)
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Still undefeated in the league and on the back of four consecutive wins, Serie A champions Juventus host improving Atalanta BC on Wednesday night in Turin.
Both teams sealed qualification for the Champions League last 16 a week ago and each followed up the feat by registering a comprehensive league win at the weekend.
We say: Juventus 2-1 Atalanta BC
After finally shaking off their malaise to record a famous triumph at Anfield and now back-to-back wins, Atalanta travel to Turin in reasonable hope of an upset.
However, Andrea Pirlo's side also look to be clicking into gear and can continue their momentum going into a packed programme ahead of the winter break.
Our tipster partners are predicting a double chance bet on a home win or an away win.
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Genoa vs. AC Milan (Wednesday, 7.45pm)
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Rolando Maran's success-starved Genoa welcome unbeaten AC Milan in trepidation on Wednesday, as the league leaders seek to build upon a late fightback which kept their defeat-free Serie A record intact on Sunday.
After that 2-2 draw with Parma at San Siro, which kept the Rossoneri top of the table ahead of a fierce chasing pack, they now meet a toiling team that languishes in the relegation zone on just six points so far.
We say: Genoa 0-2 AC Milan
If Genoa are to mount an end-of-year comeback, it is unlikely to start here. Upcoming fixtures against sides just above them are a more realistic aim, rather than this fixture in which coach Rolando Maran is just likely to batten down the hatches.
Even a changed Milan XI can recover from their weekend stumble to put the Grifone to the sword at Marassi, though it may not be a totally straightforward task in the absence of important injury-affected players.
Our tipster partners are predicting an away win.
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Spezia vs. Bologna (Wednesday, 7.45pm)
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Bologna travel to Liguria on Wednesday, looking to bounce back after their crushing 5-1 loss at the hands of rampant Roma, while hosts Spezia also suffered a heavy defeat last time out - losing 4-1 away to bottom side Crotone.
The Bianconeri return to their renovated home ground, Stadio Alberto Picco, for the first time this campaign, as they meet Sinisa Mihajlovic's side - which was sent into a training retreat after their weekend humbling.
We say: Spezia 2-2 Bologna
It may not prove a fairytale homecoming for Spezia this week, as the stands will be near-empty and they may not record the result they most desire - a first home win of the campaign.
With both sides conceding goals at a rate of around two per game, it seems fair to suggest that a score draw is the most probable outcome in the picturesque port of La Spezia.
Our tipster partners are predicting a double chance bet on a home win or an away win.
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Parma vs. Cagliari (Wednesday, 7.45pm)
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Parma host Cagliari on Wednesday night with both sides hoping to improve their league form and climb the Serie A table.
The home side have scored just three goals at home all season, while a 3-2 away victory against Torino in October has been Cagliari's only triumph on the road.
We say: Parma 1-1 Cagliari
Parma have only won one of their last eight games against Cagliari in Serie A, while the visitors have conceded 14 goals from their six away matches this season – the second highest in the division. Both teams have struggled to find form recently and with little to separate the two sides, we could see another draw on Wednesday.
Our tipster partners are predicting a double chance bet on a home win or an away win.
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Inter Milan vs. Napoli (Wednesday, 7.45pm)
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Scudetto-chasing Inter Milan host potential title rivals Napoli this Wednesday in a mouthwatering midweek clash at San Siro.
Antonio Conte's side calamitously crashed out of Europe last week - while Napoli progressed in the Europa League - but now have their eyes fixed on further closing the gap to AC Milan at the top of the Serie A table following four wins on the spin.
We say: Inter Milan 2-1 Napoli
Inter's irrepressible attack just cannot be repelled - unless you happen to be Shakhtar Donetsk - while high-flying Napoli have also scored for fun this season.
Goals seem to be guaranteed then, but Inter's marginally greater big-game nous can help them claim a valuable three point haul against one of their direct rivals for Serie A supremacy.
Our tipster partners are predicting a double chance bet on a home win or an away win.
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Hellas Verona vs. Sampdoria (Wednesday, 7.45pm)
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Hellas Verona head into their Serie A encounter with Sampdoria on Wednesday evening hoping to move within one point of the top-four with a victory.
Sampdoria, meanwhile, have lost four of their last six league matches and have failed to keep a clean sheet since October.
We say: Hellas Verona 2-0 Sampdoria
Verona have proved this campaign that they are a strong Italian outfit who are looking towards the top end of the table with the hope of moving into the top four. Sampdoria, meanwhile, need to pick up points if they are to move clear of the Serie A drop zone. The home side, who are in good form, should have enough quality to secure the three points.
Our tipster partners are predicting a double chance bet on a home win or an away win.
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Fiorentina vs. Sassuolo (Wednesday, 7.45pm)
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Sassuolo have exceeded all expectations under Roberto De Zerbi this season - currently sitting fifth in the Serie A standings - and travel to Florence this Wednesday aiming to pick up another three points at the expense of struggling Fiorentina.
Despite a recent change of management, La Viola are now only three points clear of the relegation zone after a 3-0 thumping by Atalanta at the weekend and are finding goals incredibly hard to come by.
We say: Fiorentina 1-1 Sassuolo
Ambitious Sassuolo have stayed on the coat tails of Serie A's well-resourced big boys by taking care of business against the league's lesser lights.
Sadly for a one-time member of Serie A's 'Seven Sisters', Claudio Prandelli's current Fiorentina team can now be described as such - so the enterprising Neroverdi can take home at least a point ahead of a tough upcoming fixture list.
Our tipster partners are predicting a double chance bet on a home win or an away win.