City were in complete control from the moment they took the lead after just 97 seconds, when Leroy Sane tucked home from close range to mark his first start of the season.
Find out how all of the action unfolded courtesy of Sports Mole's minute-by-minute updates below.
Well, Pep Guardiola has kept us guessing with his team selections so far this season and he switches things up again here, with a number of players who were out of favour at the start of the campaign being given their chance after the international break.
The likes of Nicolas Otamendi and Leroy Sane are amongst those, with both having been left out of the team recently despite enjoying brilliant seasons last term.
Sane and Sterling will accompany him in the front three - which has a familiar feel to it from last term - with the latter having overcome the back problem which forced him out of England duty to start today.
Riyad Mahrez drops to the bench alongside Stones, Gundogan and Jesus, while Mendy misses out entirely - much to the dismay of thousands of Fantasy Football players around the world.
That is one of three changes made by Slavisa Jokanovic, who also brings Johansen and Christie into the team.
The Serbian is the Premier League's joint top-scorer with four goals in as many games, and he now has 16 league goals since his debut for the club in February - more than any other player in the top two tiers of English football during the same period.
The 1-1 draw against Wolves represents City's only dropped points so far this term, and Fulham could pose similar problems as an ambitious, free-spending promoted team not afraid to attack.
An early-season draw with Everton proved to be a minor blip on that occasion as City went on to amass an unprecedented points haul, and Pep Guardiola will be hoping for a similar story this time around.
The dropped points against Wolves is the only blemish on their record so far this season, and aside from that they have looked as impressive as ever as they bid to become the first team in a decade to retain the title.
Big teams such as Chelsea and Arsenal have been comfortably swept aside in the Community Shield and Premier League, before City thrashed Huddersfield 6-1 and battled to a 2-1 triumph over Newcastle in their most recent outing.
Indeed, their impressive home record stretches significantly further back than that, with only one defeat in their last 33 home league games, including 18 wins and 68 goals scored in the last 20.
Guardiola has not lost to a newly-promoted team since April 2011 during his time in charge of Barcelona, while you have to go back to February 2007 for Man City's last defeat at home to a promoted team.
City have won all eight of their Premier League matches in September under Guardiola, who himself is unbeaten in his last 42 competitive matches in the month, stretching back to September 2010.
Aside from the aforementioned fact that Wolves have already taken points off City this season, Fulham have also looked more than capable of bloodying some noses back in the top flight with seven goals scored in their opening four games.
However, balance is an area where they are lacking so far, with only West Ham and Huddersfield having conceded more goals than the Cottagers.
Indeed, at either end games involving Fulham so far this season have seen 16 goals, which is a joint league-leading figure alongside Arsenal.
Fulham led 2-0 against Brighton last time out, but let Glenn Murray back into the match and he scored twice for the hosts to turn what looked like successive Premier League wins into just a point.
Improvement is needed, then, but the early signs have been promising with the summer signs settling into life at the club quickly and looking at home in the Premier Legue.
The Cottagers have won only one of their last 12 Premier League away games and have just one point from their two such games so far this season.
I cannot see past a home win in this match, and fairly comfortably too. Fulham have good players and are capable of hurting City, but if they try to attack then there will only be one winner.
SPORTS MOLE SAYS: Man City 3-1 Fulham
Another victory would would make it City's best-ever run against Fulham, having never beaten the Cottagers in six successive meetings.
Fulham have now lost heir last three visits to the Etihad, with their most recent victory coming in a 3-1 win in 2009 when Clint Dempsey scored twice - one of only four wins in the Premier League era for Fulham.
MAN CITY STARTING XI:Ederson, Walker, Delph, Laporte, Otamendi, Fernandinho, Silva (C), Bernardo, Sane, Sterling, Aguero
FULHAM STARTING XI: Bettinelli; Christie, Odoi, Mawson, Sessegnon; Johansen, McDonald, Seri; Vietto, Mitrovic, Schurrle
Fulham had actually made a good start to the match, but with just 97 seconds on the clock they find themselves behind! Seri gives the ball away in a dangerous area and Fernandinho immediately pounces on it to leave City with a three-on-one scenario.
Fernandinho works it perfectly, playing the ball into the box which Sane tucks away from close range.
This match has started at a brilliant tempo, and already Fulham look wide open on the counter-attack.
18 – Leroy Sane has had a hand in 18 goals in his last 16 Premier League games at the Etihad Stadium (6 goals, 12 assists). Return. #MCIFUL pic.twitter.com/o519u3Fsq2— OptaJoe (@OptaJoe) September 15, 2018
Bernardo keeps it alive and tries to squeeze an effort of his own in at the near post seconds later, but Bettinelli is there again.
David Silva finishes it off - his 50th Premier League goal, no less - but the beauty was in the buildup with a string of passes. Sterling plays the ball down the right channel for Bernardo, who shows really good strength to keep hold of the ball on the byline before cutting it back to Aguero. The Argentine can't get the desired contact on his finish, but Silva is following in and takes a touch before lashing it in off the bar from close range.
Indeed, City could and should be further ahead having dominanted proceedings so far, slicing FUlham open almost at well and reveling in the attacking tactics from the visitors. It has been admirable from Fulham, but not the smartest tactics.
The Germany international applied the finish touch from close range after being found by Fernandinho, who was so sharp to pounce on a misplaced Seri pass and launch a three-on-one attack.
Bernardo's low pass into the box was initially intended for Aguero, but he fuffed his ines and it broke into the path of Silva, who lashed it home from close range.
This is far too easy for Man City as Aguero picks the ball up in space on the right flank and darts straight at the defender before dropping a shoulder and reaching the byline. His ball across the face of goal finds Sterling waiting, and he is left with the easiest of finishes.
City took the lead after just 97 seconds and were in complete control from that moment onwards, with David Silva and Raheem Sterling adding to Leroy Sane's opener as Pep Guardiola's side took all three points.
Thank you very much for joining Sports Mole for today's match as Man City ease to a convincing victory over Fulham. I will leave you with our match report, and be sure to stick around for reaction too.
From me, though, it is goodbye for now!