Neither side has much to play for heading into this weekend's clash, with Freiburg not able to catch seventh-placed Hoffenheim, while Schalke sit down in 11th spot in the table.
Freiburg were in the mix for a top-seven finish when they recorded a 2-1 win over Hertha Berlin on June 16, but last weekend's 3-1 defeat at Bayern Munich proved to be extremely damaging.
Indeed, the loss, coupled with results elsewhere, left Christian Streich's side in eighth spot in the table, four points behind seventh-placed Hoffenheim with just one game left.
Freiburg will finish eighth providing that they better Eintracht Frankfurt's result against basement side Paderborn, which would be their highest position since the 2016-17 campaign.
All in all, it has been a successful season for Breisgau-Brasilianer, and they will be determined to post their 13th Bundesliga victory of the campaign before signing off for a few months.
Schalke, meanwhile, have been in rotten form since resuming their season in the middle of May. Indeed, seven defeats from nine matches has seen them slide into the bottom half of the table.
David Wagner's side, who lost 4-1 at home to Wolfsburg last weekend, have not actually been victorious in the Bundesliga since January 17, which is simply too long for a club of their ilk.
Schalke are currently 11th in the table, two points behind 10th-placed Hertha Berlin, meaning that a top-half finish is still on the cards, largely due to their form in the first half of the campaign.
The Royal Blues have only finished outside of the top 10 in the Bundesliga in one of the last eight seasons, while they claimed second in 2017-18, which shows how far they have fallen.
Freiburg Bundesliga form: DLWDWL
Schalke Bundesliga form: LLDDLL
Youngsters Can Bozdogan and Ahmed Kutucu have both been involved for the club in recent weeks and that is again expected to be the case this weekend with the former available again after a suspension.
Freiburg possible starting lineup:
Flekken; Schmid, Lienhart, Heintz, Gunter; Kwon, Abrashi, Hofler, Grifo; Petersen, Holer
Schalke possible starting lineup:
Nubel; Becker, Kabak, Oczipka, Miranda; Caligiuri, McKennie, Schopf, Bozdogan; Kutucu, Matondo
We say: Freiburg 2-0 Schalke
Both teams will be desperate to end their seasons with a win, but we are finding it difficult to look past the hosts, backing them to record a 2-0 victory. Schalke have struggled badly since returning to action in May, but Freiburg had won two out of three before losing to Bayern last weekend.