The Magpies recorded a 2-1 victory away at Aston Villa in midweek to take them four points clear of the Premier League relegation zone.
Chelsea are unbeaten in six matches, but manager Rafael Benitez will be disappointed with his side's recent form.
The European champions have squandered two-goal leads in recent weeks against Southampton and Reading respectively and Benitez will be hoping that the Stamford Bridge outfit can return to winning ways on Saturday.
Newcastle United: LLLDLW
Possible starting lineups:
Newcastle United: Krul; Coloccini, Santon, Debuchy, S.Taylor; Perch, Cabaye, Sissoko, Gutierrez, Gouffran; Cisse
Chelsea: Turnbull; Ivanovic, Cole, Cahill, Terry; Bertrand, Ramires, Lampard, Mata, Oscar; Ba
Sports Mole says: 1-2