Spurs vs. West Brom (Sunday, 12.00pm)
Spurs have lost three games in a row to completely end any hope of a title challenge, while West Brom are winless in four and are facing a swift return to the Championship.
We say: Tottenham Hotspur 2-0 West Bromwich Albion
The pressure is slowly starting to build on Mourinho on the back of three successive league losses, two of those on home soil.
West Brom have taken points away at Man City and Liverpool this season, but Allardyce's men had their confidence battered with defeat to Sheffield United in midweek and it is difficult to see them responding here.
Wolves vs. Leicester (Sunday, 2.00pm)
Meanwhile, the home side head into the contest at Molineux on the back of a much-needed 2-1 win against Arsenal, a result which has moved the club 12 points clear of the relegation zone.
We say: Wolverhampton Wanderers 1-3 Leicester City
Despite their victory over Arsenal in midweek, Wolves rode their luck before eventually claiming the three points. With that in mind, we feel that Leicester are still playing a level above their hosts, leading us to predict a convincing win for the visitors.
Liverpool vs. Man City (Sunday, 4.30pm)
The Premier League champions host the leaders in the pick of the fixtures in gameweek 23 as Liverpool welcome title rivals Manchester City to Anfield on Sunday afternoon.
Seven points separate the two sides in the table following a poor run of form for the Reds, coupled with a relentless winning streak from Pep Guardiola's men in recent weeks.
We say: Liverpool 2-2 Manchester City
The formbook points firmly at only one result in this match - a Manchester City victory to nil. Liverpool have struggled to score or win at home recently, whereas Man City's defensive record is just as impressive as their relentless winning streak.
However, look a little deeper and there is more cause for optimism for the hosts, who will be welcoming three crucial players back into their side and taking on a team who play in an entirely different way to the teams Liverpool have underperformed against in recent weeks. Add to that Man City's woeful record at Anfield and suddenly the tale of the tape begins to look much more even.
These are almost always entertaining, breathless affairs and we are hoping for an absorbing contest, which has not always been the case in big-six showdowns this season. At the end of it all, though, we are expecting the spoils to be shared in what would be a better result for Man City than Liverpool given the difference between the two sides in the table.
Sheff Utd vs. Chelsea (Sunday, 7.15pm)
Chelsea will be looking to maintain their impressive start to life under Thomas Tuchel when they take on Premier League basement boys Sheffield United at Bramall Lane.
The Blues beat Tottenham Hotspur 1-0 on Thursday to keep their momentum going, while the Blades have also found some form over the past few weeks.
We say: Sheffield United 0-2 Chelsea
Chelsea are climbing the division under Tuchel thanks to seven points from nine since the German replaced Lampard in the Stamford Bridge dugout.
Sheffield United have been in good form themselves, picking up as many league wins in their last five matches as they did in the previous 27.
The Blades have also won three of their four home Premier League matches against Chelsea, including a 3-0 triumph last season, but we cannot see past a Blues victory on Sunday.