Meanwhile, the home side head into the contest at Molineux on the back of a much-needed 2-1 win against Arsenal, a result which has moved the club 12 points clear of the relegation zone.
Leicester collected just one point from games against Everton and Leeds United, putting the pressure on Brendan Rodgers and his squad ahead of the trip to Fulham on Wednesday evening.
Despite being hindered by a number of selection issues, the Foxes were able to claim a 2-0 win in West London, moving the club above champions Liverpool.
While the Merseyside giants are only in fourth place, Rodgers deserves huge credit for Leicester's league position with 16 matches remaining in the season.
With leaders Manchester City squaring off against Liverpool later on Sunday, Rodgers knows that there is a window of opportunity to heap the pressure on each of those clubs.
Counterpart Nuno Espirito Santo has been facing pressure of a different kind with Wolves' focus now on avoiding any kind of a relegation scrap.
Although Wolves were less than convincing against Arsenal on Tuesday night, the 2-1 win ended the club's run of eight matches without a victory.
Ahead of games against Leicester, Southampton and Leeds United, Nuno will acknowledge that his players must find a way to build on their success against the Gunners.
Joao Moutinho is aiming for a second Molineux goal in the space of five days after finally ending the wait for his first strike at the club's home ground.
Wolverhampton Wanderers Premier League form: DLLDLW
Wolverhampton Wanderers form (all competitions): LLWDLW
Leicester City Premier League form: WWWDLW
Leicester City form (all competitions): WWWDLW
Despite Wolves' continued struggles when using a back four, Nuno is unlikely to tinker with the system which helped get the better of Arsenal.
Rodgers is hopeful that Wilfred Ndidi and Vardy will be back in contention after their respective spells out through injury.
Wolverhampton Wanderers possible starting lineup:
Patricio; Semedo, Boly, Coady, Kilman; Moutinho, Neves; Traore, Vitinha, Neto; Willian Jose
Leicester City possible starting lineup:
Schmeichel; Pereira, Evans, Soyuncu, Justin; Tielemans, Ndidi; Albrighton, Maddison, Barnes; Vardy
We say: Wolverhampton Wanderers 1-3 Leicester City
Despite their victory over Arsenal in midweek, Wolves rode their luck before eventually claiming the three points. With that in mind, we feel that Leicester are still playing a level above their hosts, leading us to predict a convincing win for the visitors.
Top betting tip
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