The Blues, who made history by becoming the first London club to ever win the elusive trophy, kick off their campaign with manager Roberto Di Matteo, who led them to glory last season.
The Premier League outfit head into the clash at the top of the league table, while the Old Lady boast an unbeaten record of 42 games.
Di Matteo is expected to recall Spanish winger Juan Mata after he missed out on a place in the side that drew 0-0 with Queens Park Rangers at the weekend, while defensive duo John Terry and Ashley Cole should start.
Meanwhile, Juventus boss Antonio Conte will be unable to instruct his team from the touchline after he was hit with a 10-month suspension for failing to report his knowledge of a match-fixing scandal.
Chelsea: Cech; Ivanovic, Cahill, Terry, Cole; Ramires, Mikel, Lampard; Hazard, Torres, Mata
Juventus: Buffon; Barzagli, Bonucci, Chiellini; Lichtsteiner Pirlo, Asamoah; Vidal, Marchisio; Giovinco, Vucinic
Sports Mole says: 1-2