Matt Phillips dragged an early shot wide as the visitors began strongly with Cardiff looking to break on the counter attack.
The home side then had a succession of corners, with Antony Gerrard spurning the best chance by sending his header wide.
Cardiff continued their improved performance after the break and, soon after Kenny Miller came close to giving them the lead, they were ahead after 59 minutes.
Veteran forward Kevin Phillips brought the Seasiders level after Craig Cathcart challenged David Marshall from a corner. The keeper punched clear but the ball fell to Phillips, who lifted the ball into the top corner.
Blackpool then stole the game through Matt Phillips, who first drilled home from the edge of the area before rolling in a one-on-one chance to seal the points.
Cardiff stay third despite the loss but Blackpool are closing in and have moved up to fourth thanks to the Phillips's goals.