The hosts are the only side still unbeaten in the Bundesliga and have won four of their last five.
The visiting Mainz are on a dreadful run of form following a strong start, with a run of four straight defeats ended with a draw at home to Hoffenheim before the international break.
For Bayern Javi Martinez is closing in on a return but this game will come too soon for the player who has yet to restart full training, which means that Philipp Lahm will continue in his anchor role in midfield.
Possible starting lineups
Bayern: Neuer; Rafinha, Boateng, Dante, Alaba; Lahm; Robben, Muller, Schweinsteiger, Ribery; Mandzukic
Mainz: Muller; Pospech, Svensson, Noveski, Park; Geis, Moritz, Soto; Muller, Zimling, Okazaki
Sports Mole says: 2-0