Sandro Ramirez is given his first ever Champions League start for Barcelona in the absence of Lionel Messi for Tuesday night's Group E meeting against Bayer Leverkusen.
Barcelona manager Luis Enrique has made four changes to the side which beat Las Palmas at the weekend ahead of Tuesday night's Champions League Group E meeting with Bayer Leverkusen.
The injured Lionel Messi misses the game with a knee injury, so 20-year-old Sandro Ramirez makes his first European start for the Blaugrana in the Argentine's place.
Adriano is also out of the squad, while Sergi Roberto and Marc Bartra drop to the bench, which means that Andres Iniesta, Jeremy Mathieu and Dani Alves are named in the hosts' starting XI.
Roger Schmidt also makes four changes to his side, who beat Werder Bremen 3-0 at the weekend, as rested quartet Borges Wendell, Kevin Kampl, Hakan Calhanoglu and Javier Hernandez return in place of Sebastian Boenisch, Admir Mehmedi, Julian Brandt and Stefan Kiessling.
Barcelona: Ter Stegen, Pique, Rakitic, Sergio, Alves, Iniesta, Suarez, Neymar, Mascherano, Sandro, Mathieu
Subs: Masip, Douglas, Bartra, Munir, Alba, Roberto, Gumbau
Bayer Leverkusen: Leno, Tah, Papadopoulos, Wendell, Donati, Bender, Calhanoglu, Kramer, Bellarabi, Kampl, Hernandez
Subs: Kresic, Ramalho, Kiessling, Hilbert, Mehmedi, Boenisch, Brandt
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