Diego Simeone's side are without a victory in their last three matches in all competitions, but the capital giants are just one point off the top of La Liga and will fancy their chances of overcoming 19th-placed Espanyol in the Spanish capital this weekend.
No team has drawn more La Liga matches than Atletico this season, with Simeone's team sharing the points in six of their 12 fixtures to date. The capital side have only lost once, though, and a total of 21 points has left them in fourth spot in the table, just one point off leaders Barcelona.
Incredibly, just three points separate the top seven in La Liga, and Atletico are very much in the title race at the moment despite scoring just 12 goals in their 12 matches. They have drawn their last two in the league against Alaves and Sevilla but will enter this match off the back of a disappointing defeat.
Indeed, the Spanish side went down 2-1 away to Bayer Leverkusen in the Champions League on Wednesday night, allowing Juventus to move three points clear at the top of the group.
Atletico are still well-placed to qualify for the round of 16 as they have a four-point advantage over third-placed Lokomotiv Moscow, but the manner of the defeat against Leverkusen will surely have concerned Simeone.
The capital giants could well find themselves top of La Liga at the end of the weekend should other results go in their favour, although it is difficult to see them finishing in that position come the end of the season when considering their problems in the final third of the field.
There is no getting away from the fact that it has been a disappointing start to the season for Espanyol, who are now under the management of Pablo Machin after David Gallego was sacked towards the start of October.
Machin has won three of his six matches in charge of the Catalan outfit, but a record of two wins, two draws and eight defeats this term has left them in 19th position in the table, just three points off the bottom.
No team has scored fewer La Liga goals - six - than Espanyol this term, which is an indication of their struggles. For a side that finished seventh in Spain's top flight last season, it has been an underwhelming start.
That said, the Catalan side are absolutely flying in the Europa League, where they have won three of their four matches to sit top of Group H; they thumped Ludogorets 6-0 on Thursday night, with that result following back-to-back league defeats to Athletic Bilbao and Valencia.
Atletico are undoubtedly the favourites heading into this weekend's contest, but Espanyol actually beat Simeone's side 3-0 when they last locked horns in the league towards the end of last season.
Atletico form: DDDWDD
Espanyol form: LLLWLL
Joao Felix, meanwhile, remains unavailable for Simeone's side due to an ankle problem.
Sergi Darder will be among those to return having been left out of Thursday's Europa League contest, while on-loan Benfica attacker Facundo Ferreyra should get the nod in the final third of the field.
Atletico possible starting lineup: Oblak; Trippier, Felipe, Hermoso, Lodi; Lemar, Partey, Saul, Koke; Correa, Morata
Espanyol possible starting lineup: Lopez; Espinosa, Lopez, Naldo; Gomez, Roca, Sanchez, Vila; Darder; Ferreyra, Vargas
We say: Atletico 2-0 Espanyol
Atletico are unlikely to blow Espanyol away as they are just not that type of team, but we fancy the hosts to pick up three much-needed points at the Wanda Metropolitano on Sunday afternoon.