With Real Madrid facing Barcelona in the late kickoff on Sunday, victory for Atletico would move them top of La Liga due to their superior head-to-head record over Los Blancos.
"Betis have grown a lot since the last visit to Calderon," he told reporters at a press conference. "They have competed very well in the previous league matches and certainly have suffered a taught blow on in the Europa League last Thursday.
"But it is a team that has been improving in the league. It has grown and they are playing with intensity and aggression.
"We have to play as usual it will be a tough match due to the needs. It will be a match where we'll both have needs."
Betis remain rooted to the bottom of La Liga, nine points from safety.