The visitors also go into this game on the back of a much-needed win as they overcame fellow strugglers Reims 1-0 last time out.
Monaco supporters must have been fearing the worst when Kylian Mbappe quickly put PSG in control last Friday, with the 21-year-old's first-half brace opening the floodgates for what seemed destined to be a resounding victory for the champions.
However, an inspired half-time substitution by Monaco manager Niko Kovac turned the game on its head. Kevin Volland initially pulled one back for Monaco before bagging his second after being set up by Cesc Fabregas, who demonstrated his class throughout the second period.
The former Arsenal and Chelsea lynchpin was the hero of the hour for Monaco as his penalty saw Les Monegasques come away with all three points after Abdou Diallo hauled Volland to the ground. PSG were always going to be up against it with their depleted squad, but that does not make Monaco's victory any less special.
Kovac's men boast a 100% record in the month of November having also beaten Nice and Bordeaux over the past couple of weeks, with Marseille and Montpellier the only other teams in the French top flight to have won their last three on the trot.
Incredibly, fifth-placed Monaco are level on points and goal difference with fourth-placed Montpellier - with both sides scoring 20 and conceding 16 goals thus far - and Kovac's men will no doubt be hoping that Lorient can pull off a shock result against La Paillade ahead of their showdown with Nimes.
Nimes were challenging Saint-Etienne for the worst form in Ligue 1 before taking to the field against Reims, who had started to see their results improve at a crucial time.
However, Jerome Arpinon's men managed to take an unexpected three points from their trip to the Stade Auguste-Delaune, with Renaud Ripart notching up his fifth goal against Reims as his second-half penalty ultimately separated the two sides.
Les Crocodiles had lost their last four in succession before that narrow victory - a run which saw them ship 12 goals and notch up just one - but Nimes are certainly facing an uphill battle to avoid yet another defeat against a Monaco outfit buoyed by that historic win over PSG.
However, Les Crocodiles have taken a point from their last two trips to Monaco and overcame Les Monegasques 3-1 in their most recent meeting, with this weekend's hosts winless against Nimes since 2015.
Monaco Ligue 1 form: LDLWWW
Nimes Ligue 1 form: WLLLLW
Fabregas has surely done enough to warrant a starting place this weekend, which could see Kovac drop Sofiane Diop as he reverts to his original 4-3-3 from the start of the season.
Loick Landre and Pablo Martinez will continue at centre-back in the absence of Anthony Briancon, who has a knee injury, while fellow defender Birger Meling is also out with a problem in the same area.
Monaco possible starting lineup:
Mannone; Aguilar, Disasi, Badiashile, Henrique; Tchouameni, Fofana, Fabregas; Volland, Ben Yedder, Geubbels
Nimes possible starting lineup:
Reyner; Burner, Landre, Martinez, Paquiez; Cubas, Deaux, Fomba; Ferhat, Denkey, Ripart
We say: Monaco 3-0 Nimes
Nimes can afford to be positive heading into this game given their strong set of results against Monaco over the past couple of seasons, but that is unlikely to continue here. Kovac's men will feel like they can beat anyone after putting three past PSG last week, and Les Monegasques should ease to a comfortable victory on their own turf this weekend.