The 26-year-old arrived at the Emirates Stadium in a £19m deal last month and is today given his first outing in a Gunners shirt.
Alexandre Lacazette is expected to lead the line in Arsenal's second official pre-season outing, nearly a fortnight on from their 8-0 thrashing of Boreham Wood, while Emile Smith Rowe will also feature in the attack line after being promoted to the first team by Unai Emery.
Atletico are running out for the first time this summer, meanwhile, and Diego Simeone has named a strong-looking starting lineup for the International Champions Cup tie.
Kevin Gameiro and Luciano Vietto are used up top as Simeone sticks with his favoured 4-4-2 formation, and there is also a start in midfield for recent capture Rodrigo, who joined from Villarreal in a deal that could rise past the £20m mark.
Arsenal: Leno; Bellerin, Mustafi, Holding, Kolasinac; Ramsey, Guendouzi; Nelson, Smith Rowe, Aubameyang; Lacazette
Subs: Cech, Sokratis, Mkhitaryan, Maitland-Niles, Chambers, Mavropanos, Lucas, Nketiah, Osei-Tutu, Willock
Atletico Madrid: Oblak; Juanfran, Montero, Thomas, Moya; Rodrigo, Olabe, Joaquin, Correa; Gameiro, Vietto
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