The Frenchman believes that their clash with Poyet's men will be more like a typical Premier League match than an FA Cup one.
"Poyet has done very well because he got them promotion and in a position where they can challenge for the playoffs," Wenger said.
"I have seen the game against Newcastle. They played a Premier League game.
"Brighton play out from the back, have a lot of possession and a big South American influence with their manager, the players they have, and the way they play, so you know you face a typical away game in the Premier League."
Wenger has also said that his side are fully focused on progressing into the next round of the competition.