The Latics are likely to be without Jean Beausejour for the relegation battle after he suffered a hamstring strain at The Hawthorns on Saturday.
Swansea are still aiming for a top-10 finish but have taken just three points from a possible 21 since beating Newcastle United at the beginning of March.
Possible starting lineups:
Wigan: Robles, Boyce, Caldwell, Golobart, Stam, McArthur, McCarthy, Scharner, Gomez, McManaman, Kone
Swansea: Vorm, Davies, Chico, Williams, Rangel, Britton, De Guzman, Dyer, Routledge, Hernandez, Moore
Sports Mole says: 2-1