The centre-back, who had been suffering with an ankle problem, played for the first time in three months during the Hammers' 2-0 win over Swansea City.
"It's nice being back out there and the most important thing was that we got the three points. It was a good victory on Saturday and the boys needed it," Reid told the club's official website.
"It has been 12 weeks now. It has not been the easiest 12 weeks but you get injuries as a footballer and the main thing is to get over it and deal with it. Fortunately enough I'm back fit and healthy."
Reid has made 11 appearances in all competitions for West Ham this season.