Williams says that Wales will be prepared to deal with the threat that Cyprus pose, after they beat Bosnia 2-1 in September.
"We know especially because we drew the game [against Bosnia] that we need to win this game," Williams told BBC Sport.
"If we want to do anything in the group this is one we must win. We've done a little bit of analysis [on Cyprus]. As players we get our own footage to go through, so we are aware of them.
"We know that they are a dangerous team clearly, with what happened in Bosnia."
Wales will remain top of the group with a win, ahead of their next qualifier against Belgium on November 16.