The hosts have three wins from their opening five home games but have lost two of their last three overall.
Inter's form has stuttered of late, with just one win from their last five in the league. However, they are yet to lose away from the San Siro.
The only injury concern for Udinese is Maurizio Domizzi, who is unlikely to play, while Ishak Belfodil could return for the visitors.
Possible starting lineups
Udinese: Brkic; Danilo, Domizzi, Basta, Gabriel Silva; Naldo, Lazzari, Allan, Pereyra; Muriel, Di Natale
Inter: Handanovic; Jonathan, Samuel, Nagamoto, Rolando; Juan Jesus, Cambiasso, Kovacic, Guarin, Alvarez; Palacio
Sports Mole says: 2-1