The 24-year-old picked up an elbow injury during the 2-1 defeat to Juventus in the Champions League on Wednesday night.
However, Dier has passed a fitness test to earn a place in the squad at the Vitality Stadium, though Mauricio Pochettino has opted not to risk the England star from the off.
Bournemouth, meanwhile, have made just the one change from the 1-1 draw at Leicester City last time out.
Bournemouth: Begovic; Francis, S. Cook, Ake, Daniels; Stanislas, Smith, Gosling, L. Cook; Mousset, Wilson
Subs: Boruc, Surman, Arter, King, Defoe, Fraser, Ibe
Tottenham Hotspur: Lloris; Aurier, Vertonghen, Sanchez, Rose; Wanyama, Dembele; Eriksen, Alli, Son; Kane
Subs: Vorm, Trippier, Lamela, Dier, Sissoko, Llorente, Moura
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