Tottenham lineup vs. Man United: Predicted XI for Premier League clash

Tottenham Hotspur could be without as many as 10 players for Saturday’s Premier League clash with Manchester United at Old Trafford.

Spurs’ packed treatment room includes James Maddison, Dejan Kulusevski (both knee), Mohammed Kudus (thigh), Pedro Porro, Richarlison, Rodrigo Bentancur (all hamstring), Ben Davies, Lucas Bergvall (both ankle) and Kevin Danso (toe) who are all ruled out.

Dominic Solanke (fitness) and Cristian Romero could not complete the full 90 minutes in last weekend’s 2-2 Premier League draw with Man City - a game in which Solanke scored two second-half goals - but both players are available for selection against Man United.

Micky van de Ven is also fit to return this weekend after missing Tottenham's last two games with a minor issue, but head coach Thomas Frank has revealed that Djed Spence is "touch and go" with a calf injury and a late call will be made on his availability.

Romero and Van de Ven are both expected to start at centre-back, while Spence - if fit - Destiny Udogie, Archie Gray and new signing Souza will all battle for a starting spot at full-back or wing-back, depending on the formation.

Pape Sarr will be looking to force his way back in the first XI and could either replace or link up with Conor Gallagher, Joao Palhinha and Yves Bissouma in centre-midfield.

Wilson Odobert and Mathys Tel are both in contention to earn recalls in the final third, though Randal Kolo Muani, Xavi Simons and Solanke are all likely to retain their starting spots - the latter has scored five goals in his last five appearances against Man United in all competitions.

Tottenham Hotspur possible starting lineup: Vicario; Spence, Romero, Van de Ven, Udogie; Bissouma, Gallagher; Odobert, Simons, Kolo Muani; Solanke

> Click here to see how Manchester United could line up for this contest