The attacking duo both suffered injuries during the midweek Europa League clash with Basel and will spend a few weeks on the sidelines while the North London outfit chase a top-four finish.
However, Mabbutt believes that his former team have strength in depth and does not think this setback will derail their season.
"Fortunately, Tottenham have got a very strong squad together and they have a great attitude," Mabbutt told talkSPORT. "I think we have enough strength to come through this.
"We've got strong players in the squad, a lot of players that have a lot of experience. Of course, pace is the key in a lot of games, certainly when you've got players like Gareth Bale and Aaron Lennon.
"That's an area where we've really attacked teams and caused teams problems throughout the season, but I think we've got enough players now, and they've all got some first team experience because the manager has rotated the team."
Spurs are currently third in the Premier League.