The North London outfit head to Goodison Park just one point above the Merseyside club in fourth place in the Premier League table.
"It's an important fixture for teams competing for a top four spot," Villas-Boas said in a press conference. "We hope to go there and make it as difficult as possible.
"It's been a good week for us, our team is very driven. We look good and solid and hope this will be a good game. Everton's results have been excellent and the team have really bonded to Roberto's ideas. They are playing excellent football."
Everton are currently sixth in the table.