Yet to win a Premier League home match against Tottenham Hotspur, Brentford aim to banish that curse in Saturday's 2026-27 opener at the Gtech Community Stadium.
The Bees battered Eintracht Frankfurt 7-0 in their last pre-season game, while the Lilywhites drew 2-2 with Hoffenheim behind closed doors.
Here, Sports Mole rounds up the latest team news for both sides.
BRENTFORD vs. TOTTENHAM
BRENTFORD
Out: Antoni Milambo (knee), Sepp van den Berg (abductor)
Doubtful: None
Sports Mole's predicted XI: Kelleher; Kayode, Ajer, Collins, Lewis-Potter; Sangare, Janelt; Ouattara, Jensen, Schade; Thiago
TOTTENHAM
Out: Xavi Simons (ACL), Wilson Odobert (knee), Dejan Kulusevski (knee), Mohammed Kudus (thigh), Pape Sarr (groin), Micky van de Ven (unspecified), Pedro Porro (unspecified)
Doubtful: None
Sports Mole's predicted XI: Kinsky; Gray, Senesi, Van Hecke, Robertson; Tonali, Fernandes; Moore, Gallagher, Tel; Richarlison