Gareth Bale scored three times against the league's bottom club, and the Wales international should retain his spot in the final third of the field, with Son Heung-min, Dele Alli and Harry Kane also starting.
Toby Alderweireld had fallen out of favour under Jose Mourinho, but the Belgium international has been reinstated since Mason replaced the Portuguese, and he should again feature at the back at Elland Road.
Moussa Sissoko and fit-again Matt Doherty will also be in the squad, but neither player are in serious contention to start, with Serge Aurier set to retain his spot at right-back for the North London club.
Tottenham possible starting lineup: Lloris; Aurier, Alderweireld, Dier, Reguilon; Lo Celso, Hojbjerg; Son, Dele, Bale; Kane
> Click here to see how Leeds could line up for this contest Watch the Sports Mole Football Shorts prediction for this game below:
Watch the Sports Mole Football Shorts prediction for this game below: