Mauricio Pochettino's side go into the weekend sitting fourth in the Premier League table courtesy of back-to-back victories, and another win would temporarily lift them above London rivals Chelsea, who do not play until Sunday.
However, Tottenham are missing a number of key first-team players through injury and so will not be able to field a full-strength lineup against the winless Bluebirds.
Here, Sports Mole looks at how the North Londoners could line up at Wembley.
Pochettino has limited options available to him this weekend with the likes of Eriksen, Alli, Dembele and Vertonghen all sidelined, so changes from the midweek defeat to Barcelona may be minimal.
Captain Hugo Lloris has now recovered from his injury and will start in goal despite his shaky showing in the Champions League, while in front of him Danny Rose is likely to come in for Ben Davies at left-back.
Eric Dier is also pushing for a recall to the starting lineup - most likely in place of Victor Wanyama - with Harry Winks having been trusted to play the full 90 minutes against Barcelona on Wednesday night.
Harry Kane and Erik Lamela were both on the scoresheet at Wembley and will start again in what is expected to be an unchanged front four, with Moussa Sissoko the only player pushing for inclusion in that area of the field considering Tottenham's injuries.