The Terriers have collected just two points from a possible 18 so far, seeing them prop up the rest of the division with the joint-worst goal difference.
There are a number of selection decisions to be made by boss David Wagner for this fourth home match of the season, with the German admitting to being unhappy with the "big mistakes" made during last week's 3-1 loss at Leicester City.
Here, Sports Mole looks at how Huddersfield could line up for this weekend's match.
Out: Ramadan Sobhi (knee)
Huddersfield's only confirmed absentee for Saturday's showdown is Egyptian winger Sobhi, as Jonathan Hogg is back involved following his three-match ban for a needless sending-off against Cardiff City.
Hogg watched on from the bench at the King Power Stadium, with Wagner favouring a five-man backline, and the German is expected to go with the same formation for the visit of Spurs.
Laurent Depoitre has yet to get off the mark in front of goal this season, but he claimed an assist on his first start of the season last time out and could retain his spot up top on Saturday.