Longeran starts as the Trotters, who ended a run of three defeats when they earned a point at Sheffield Wednesday at the weekend, expect to lose the services of first-choice shot-stopper Adam Bogdan for up to eight weeks with a broken finger.
Dougie Freedman must deal with a depleted backline for the visit of Rotherham, who sit three places above the Lancashire club in the table, as both Kevin McNaughton (illness) and David Wheater (back) are absent.
Rob Milsom is also left out for the Yorkshiremen as he continues his path to full fitness.
Wanderers currently find themselves two points from safety, while their opponents could climb into the top half of the Championship with victory at the Macron Stadium.
Bolton Wanderers: Lonergan, Ream, Dervite, Mills, Moxey, Spearing, M Davies, Pratley, Danns, C Davies, Mason
Rotherham United: Collin, Richardson, Morgan, Arnason, Skarz; Taylor, Smallwood, Green, Wordsworth; Becchio, Derbyshire