It is the first time both players have featured from the off in a La Liga game this term, although Los Blancos will be without two of their other star forward players as both Cristiano Ronaldo and Gareth Bale are absent.
Benzema has slowly been integrated back into the fold this term, featuring for just 26 minutes in the league and a little over an hour in the Champions League win over Sporting Lisbon last time out, while Rodriguez has featured from the bench on two occasions.
Espanyol: Diego Lopez; J.Lopez, D.Lopez, O.Duarte, Sanchez; Perez, Diop, Roca, Piatti; Baptistao, Moreno
Real Madrid: Casilla; Carvajal, Pepe, Ramos, Marcelo; Casemiro, Modric, James; Lucas, Benzema, Asensio
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