The Spanish giants meet at the Bernabeu on Saturday evening, but Bale is a serious doubt after picking up a hip problem.
That said, Neymar has said that Los Blancos have the squad to cope with the loss of key players.
"The injury to Gareth Bale? He has real quality, but even if he isn't able to play – Real Madrid have a great squad over there with some very important players," he told reporters.
Both Neymar and Bale arrived in Spain last summer.