The Super Eagles edged out Rwanda in the qualifiers this time around before they emphatically thumped Liberia 8-3 on aggregate to seal their progress into the finals.
With coach Stephen Keshi in charge they have a man who won the competition as a player the last time that Nigeria triumphed in 1994.
Only six members of the squad play club football in their home country, with the other 17 players plying their trade across Europe.
Players to watch out for:
Nigeria's most-capped player has been on the international scene for 12 years and is a veteran when it comes to the AFCON. His no-nonsense style of defending will be familiar to Everton fans following a six-year spell at Goodison Park.
Moses has been something of a talisman for Chelsea this season, popping up with goals when the team most needs them. His skill out on the wings will come in handy for Nigeria, but it's his knack of being in the right place at the right time in the box that could make a real difference.
Previous best: Winners 1980, 1994
Odds to win outright: 9/1
Sports Mole says: Quarter-finals