New England vs. Nashville (Thursday, 12.00am)
We say: New England Revolution 1-0 Nashville SC
New England seem to come alive just in the nick of time, but there is no denying how deep they are offensively as 10 different players have at least a goal this season, and they have scored in every one of their home games so far this year.
Nashville have shown that they are a strong side both on and off the ball, but they are missing some critical pieces to their team, and without their defensive anchor, Walker Zimmerman, Willis could see a lot of pressure against a team who have scored 10 goals in their last four home fixtures.
Columbus Crew vs. DC United (Thursday, 12.30am)
Meanwhile, Columbus Crew will be aiming to preserve their unbeaten streak on home turf this term, which currently stands at seven matches.
We say: Columbus Crew 2-1 DC United
The game promises to be an enthralling affair as two very good teams go head-to-head. Columbus Crew will back themselves to take advantage of the visitors' frailties on the road, and we are tipping them to claim a narrow victory in the end.
Philadelphia vs. Toronto (Thursday, 12.30am)
Looking to stretch their Major League Soccer unbeaten run to six games, Toronto go on the road on Wednesday for a trip to Philadelphia Union.
The Canadian side have bounced back from a six-game losing run to quickly move off the foot of the Major League Soccer Eastern Conference table, while their hosts have slipped down to fifth spot after a disappointing patch of form.
We say: Philadelphia Union 1-2 Toronto
While Philadelphia Union have had the stronger season of the two sides so far, we see Toronto's far superior form seeing them to another impressive result on Wednesday.
The Reds come into the match with plenty of momentum having reversed their fortunes to climb the table, while their opponents have struggled and fallen out of reach of the top three, and we would not be surprised to see Toronto continue their improvement with another win.
Montreal vs. Atlanta (Thursday, 12.30am)
On the other hand, the home side will relish an opportunity to return to winning ways on home turf following three consecutive away losses.
We say: CF Montreal 1-0 Atlanta United
The away side have got the better of their hosts more often than not, but their form heading into the contest suggests that the hosts have a chance of turning the tide. We are tipping CF Montreal to emerge victorious in what should be a fascinating encounter.
NY Red Bulls vs. Cincinnati (Thursday, 1.00am)
New York Red Bulls take on FC Cincinnati in the MLS Eastern Conference on Wednesday, with both sides looking to keep pace with the play-off positions.
NY Red Bulls and Cincinnati find themselves four points and eight points adrift of CF Montreal respectively, with this upcoming clash representing both teams' game in hand.
We say: New York Red Bulls 2-1 FC Cincinnati
We expect NY Red Bulls to have too much quality for Cincinnati on Wednesday, although the visitors have enough about them to keep things tight.
Although Stam's side do not win many matches, four of their last six games have ended as draws, so it would not be too surprising if Struber's side are on the right end of a late winner this time around.
Orlando City vs. Inter Miami (Thursday, 1.00am)
After breaking a losing run recently, the visitors will come into the game with renewed confidence, while both sides will be hoping to get one over on the other in the battle between Florida's two MLS sides.
We say: Orlando City 2-1 Inter Miami
While Inter Miami look to have turned a corner, Orlando have been a formidable outfit for almost the entirety of the campaign so far and could be a step too far for the Herons in the current circumstances.
The Lions did well to bounce back from a heavy defeat last time out, and we would expect them to collect three more points in their bid to keep hold of a spot at the top end of the table.
Chicago Fire vs. NY City (Thursday, 1.00am)
The Pigeons wrapped up their three-game homestand with a 4-1 win over the Columbus Crew, while Chicago drew 1-1 versus the Philadelphia Union.
We say: Chicago Fire 2-3 New York City FC
The Fire have scored multiple goals in four of their last five matches played at Soldier Field, and while they seem to start brightly, they have not shown that they can maintain their early momentum throughout a match.
New York have been as good offensively as any side in MLS over the past few weeks, but they seem to be a little weaker in transition away from home, which has cost them lately as they have conceded multiple goals over their last two road games, but their goalscoring ability should carry them through on Wednesday.
Austin vs. Houston (Thursday, 2.00am)
Austin are eight points behind seventh-placed Real Salt Lake, with Houston only three points behind seventh spot, further incentivising a win for the visitors.
We say: Austin FC 0-1 Houston Dynamo
We believe Houston's winless run could come to an end on Wednesday, with Ramos's side undoubtedly possessing greater quality than the newly-formed Austin.
However, the hosts could be tough to break down, so Houston must remain patient and put their current poor form to the back of their minds if they are to gain the positive result which they require.
Seattle vs. Dallas (Thursday, 3.00am)
We say: Seattle Sounders 1-0 Dallas
Seattle have not lost three straight regular-season fixtures since 2019, and even with all of their regulars who are missing, they have still had plenty of chances to score, and luckily for them, they are playing a Toros team who have conceded 16 goals on the road this season.
Dallas have been held off the scoresheet on five occasions this year away from home, and when visiting Seattle, they have been blanked five times and have been outscored by the Sounders 14-1 in their last five trips to Lumen Field.
Los Angeles vs. Kansas (Thursday, 3.30am)
Los Angeles FC can extend their unbeaten run at home to six games when they host Sporting Kansas City on Wednesday at Banc of California Stadium.
The Black-and-Gold conceded an injury-time goal to draw Minnesota United 2-2 in their last fixture, while KC came up short versus Dallas, losing 2-1.
We say: Los Angeles FC 1-2 Sporting Kansas City
Los Angeles are a tough team to play at home, and they have plenty of firepower to match a well-balanced Kansas City side, but they seem to struggle when it comes to maintaining that high intensity throughout a full 90-minutes.
Kansas City might have just had their worst outing of the season, but they know how to bounce back, and they have always been at their best against teams in the top half of the table, having yet to lose to a team currently in a playoff position.
Portland vs. Earthquakes (Thursday, 3.30am)
The San Jose Earthquakes shall attempt to pick up consecutive victories on Thursday when they travel to Providence Park to take on the Portland Timbers, who have been suffering from mixed consistency as of late.
The Quakers have proven to be difficult to defeat recently, while Portland must look to bounce back from a 4-1 defeat against LA Galaxy as they search for their first victory in two games.
We say: Portland Timbers 2-2 San Jose Earthquakes
Portland Timbers have made their home ground a difficult place for anybody to visit, and considering the fact that San Jose have not been picking up regular victories as of late, they will likely make life tough for the visitors.
However, San Jose have been in consistent form in terms of picking up points, albeit not always with victories, which is why they will likely battle it out to a draw.