Chris Smalling makes way for 18-year-old defender Cameron Borthwick-Jackson for his first United start, while Guillermo Varela replaces Matteo Darmian at right-back, with both defenders missing having suffered injuries in their side's 3-2 Champions League defeat by Wolfsburg on Tuesday evening.
Bournemouth: Boruc; Smith, Cook, Francis, Daniels; Ritchie, Surman, Arter, Gosling, Stanislas; King
Subs: Federici, Pugh, Rantie, Kermorgant, Distin, Murray, O'Kane
Manchester United: De Gea; Varela, McNair, Borthwick-Jackson, Blind; Carrick, Fellaini; Lingard, Mata, Memphis; Martial
Subs: Romero, Jones, Tuanzebe, Young, Schneiderlin, Pereira, Powell
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