Man Utd vs. Fulham (Tuesday, 6.00pm)
The Red Devils, who will be attempting to secure second spot in the table, have suffered defeats in their last two league matches to Leicester City and Liverpool, while Fulham are on a three-game losing run in England's top flight and will be relegated back to the Championship for the 2021-22 campaign.
We say: Manchester United 2-0 Fulham
There is not an awful lot riding on this match for either side, but Man United will be determined to tie up second spot in the table. Fulham are certainly capable of causing the Red Devils problems, but we are finding it difficult to predict anything other than a routine victory for Solskjaer's team.
Southampton vs. Leeds (Tuesday, 6.00pm)
The hosts picked up a 3-1 win over already-relegated Fulham on Saturday, while Leeds thrashed Burnley 4-0 away from home to maintain their position in the top half of the Premier League table going into the final two games of the season.
We say: Southampton 1-3 Leeds United
Both sides come into this game in positive runs of form, but we see the visitors having too much for Southampton on Tuesday, particularly given their form in front of goal.
The Peacocks have netted seven goals in the last two games and definitely have the tools to hurt the Saints, while their defence has also looked improved recently, seeing them to a strong finish in the Premier League.
Brighton vs. Man City (Tuesday, 7.00pm)
Brighton & Hove Albion take on champions Manchester City in the Premier League on Tuesday, with the Citizens looking to build momentum ahead of their Champions League final clash against Chelsea towards the end of May.
Brighton, meanwhile, have already secured their safety for a fourth successive season, so they are simply aiming to finish as high in the table as they possibly can.
We say: Brighton & Hove Albion 1-3 Manchester City
Much will depend on which side Guardiola selects, but either way we expect his group of players to secure a 13th consecutive away win in the Premier League.
Any fringe players included will want to lay down a marker as they look to earn a place in the Spaniard's thoughts ahead of the Champions League final, while City's key players will want to continue their excellent form.
Chelsea vs. Leicester (Tuesday, 8.15pm)
Chelsea take on Leicester City at Stamford Bridge in the Premier League on Tuesday, with both sides looking to increase their chances of finishing in the top four of the table in order to qualify for next season's Champions League.
Leicester defeated Chelsea 1-0 to win their first ever FA Cup at Wembley on Saturday, so it will be a quick turnaround for both teams.
We say: Chelsea 1-0 Leicester City
We can envisage Chelsea gaining revenge against Leicester on Tuesday, with the Foxes likely to be lacking the same intensity that they produced at Wembley, despite the amount riding on this fixture, too.
It is likely to be another cagey, low-scoring affair with both sides prioritising stability in defence, so scoring the first goal will be crucial.