However, Van Persie has revealed that he always found the Italian international to be pleasant, both on and off the pitch.
"I have always been a fan of Balotelli. He is quick, strong and is courageous. He has all the qualities a striker needs to succeed at the highest level," Van Persie was quoted as saying by NUsport.
"And he really is a nice guy as well. We spoke to each other every now and then when he still played at Manchester City.
"You have people who initially look like nice guys, but turn out to be different in the end. Balotelli is the exact opposite. He might not look like a nice lad, but he definitely is."
Van Persie will come up against Balotelli tomorrow night when Holland take on Italy in Amsterdam.