Rooney missed last weekend's draw with Stoke, a game where Hernandez limped off after seven minutes.
Both players then missed out on United's Champions League 3-3 draw with Basel, their first game without a win at Old Trafford in 20.
However, Red Devils boss Sir Alex Ferguson has told the club's website that both players are ready for the visit of Norwich.
"Wayne and Hernandez are fit for tomorrow," Ferguson said.
"They trained very well yesterday, which is pleasing."
Rooney, 25, is the Premier League's top scorer so far this season with nine, one ahead of Manchester City's Sergio Aguero.