Brandon Williams, Rhys Williams and Sam Surridge have been called up to the England Under-21 squad.
The trio are included in Aidy Boothroyd's squad for the first time ahead of the Euro 2021 qualifiers against Andorra and Turkey.
Their call-ups come after Japhet Tanganga, Tariq Lamptey, Reiss Nelson and Rhian Brewster pulled out.
Manchester United left-back Brandon Williams has made 38 appearances for the club, including two in the Carabao Cup this season.
Boothroyd's side need four points to secure top spot in Group Three and they travel to Andorra on Wednesday before hosting Turkey at Molineux on Tuesday, October 13.