The Spaniard started his Premier League career impressively, but a run of 14 matches without a goal means that his place in the squad is under threat ahead of this summer's tournament.
"It's my dream to be involved in the World Cup - it would be great and is something I am fighting for," Negredo told members of the media.
"Not playing regularly here means the national manager has not seen much of me, but I won't give up. Quite the contrary, I am full of optimism. I believe he will still have confidence in me."
Negredo has started just once in City's previous five games.