Brighton, meanwhile, have already secured their Premier League safety for a fourth successive season, but will be looking to finish as high as possible in the table.
Here, Sports Mole rounds up all of the latest team news for both clubs.
BRIGHTON & HOVE ALBION
Sports Mole's predicted XI: Sanchez; White, Webster, Burn; Gross, Lallana, Bissouma, Moder; Trossard, Jahanbakhsh; Welbeck
Sports Mole's predicted XI: Ederson; Cancelo, Stones, Dias, Mendy; Silva, Fernandinho, Foden; Mahrez, Jesus, Torres
Watch the Sports Mole Football Shorts prediction for this game below: