Pep Guardiola rested a number of key men for Tuesday's goalless draw with Porto, a result that makes certain of top spot in Champions League Group C, but he is expected to field his strongest-available side against lowly Fulham this weekend.
Here, Sports Mole rounds up City's latest injury and suspension news ahead of the match at the Etihad Stadium.
Status: Major doubt
Type of injury: Knee
Possible return date: December 5 (vs. Fulham)
Aguero suffered another knee injury setback last week and has missed City's last two games. Guardiola is unwilling to take any risks on the striker's fitness and it may well be that he spends another spell on the sidelines.
MANCHESTER CITY'S SUSPENSION LIST
Man City have no players suspended for their showdown with Fulham.