Aguero scored a brace to help City beat West Ham United 3-1 in the Premier League yesterday, but their defeat to Bayern Munich by the same scoreline in their last Champions League outing means that they would drop to third in Group D if they lose on Wednesday.
The victory over the Hammers was City's first away win of the season, and Aguero has urged his side to carry on picking up maximum points on their travels, starting against Moscow.
"We have to win, don't we? It's an important three points because then we play them (at) home. We won against West Ham away in the Premier League and now we have to win away in Moscow as well," Aguero told City TV.
"It was very important to win against West Ham and now we have to keep winning away matches. We have to continue."
City are currently fourth in the Premier League table, three points behind first-placed Arsenal.