Young goalkeeper Alphonse Areola starts in place of Salvatore Sirigu, while experienced heads Siaka Tiene, Zoumana Camara and Sylvain Armand start in defence.
Zlatan Ibrahimovic and Ezequiel Lavezzi start in attack, with Kevin Gameiro left on the bench against his former club.
Ludovic Giuly starts for Lorient alongside Kevin Monnet-Paquet.
Lorient: Audard, Ecuele Manga, Le Lan, Lautoa, Gassama, Jouffre, Lemina, Barthelme, Robert, Giuly, Monnet-Paquet
PSG: Areola, Tiene, Camara, Armand, Van der Wiel, Matuidi, Chantome, Verratti, Pastore, Ibrahimovic, Lavezzi