Earlier in the season, Liverpool suffered a 2-1 loss at the Etihad Stadium.
"It's a totally different picture when we play at home," the Liverpool Echo quotes Mignolet as saying. "With the support from the fans we can get the three points.
"We take one game at a time and it's why the next one is important. The one away from home against Man City – we won't think about that when it's kickoff time on Sunday.
"It's about making sure we put in the performance that we want to and we do our jobs the best we can do this Sunday."
Liverpool have five games left to play in their campaign, while City have seven.