Not even the highly-anticipated return of Jamie Vardy could help propel Leicester to victory at Molineux on Sunday, as Brendan Rodgers's men fell further behind Manchester City in the Premier League title race with a 0-0 draw in the West Midlands.
With only a solitary win to boast from their last four Premier League matches, the third-placed Foxes are now seven points off the pace having played a game more than Man City, and their recent underwhelming form could end up proving costly in the battle for glory.
The King Power faithful can be confident of a turnaround in fortunes now that Vardy is back and ready for action again, but his absence has been well and truly felt by Rodgers's side, who temporarily turn their attention to another realistic shot at a piece of silverware this season.
Two trips to Championship sides in Stoke City and Brentford saw Leicester score seven goals and concede just one in a pair of routine victories, and they remain on course to better last season's finish in the FA Cup, where Chelsea dumped them out in the quarter-finals.
Still yet to taste success in England's most prestigious competition, the current crop at Leicester will certainly feel capable of etching their names into the club's history books this season, but Brighton's recent form has them daring to dream as well.
Largely down to an inspired performance from Robert Sanchez in the Brighton goal, this week's visitors managed to claim a share of the spoils from their clash with Burnley at Turf Moor.
Lewis Dunk's header was cancelled out by a rare goal from Johann Berg Gudmundsson on the day, with Brighton unable to follow up their historic wins over Tottenham Hotspur and Liverpool with a third triumph on the bounce, but their recent results still make for excellent reading.
Now unbeaten in their last five Premier League matches - winning three and drawing two, with four clean sheets to boot - Brighton's survival bid is gathering pace, and their results are starting to reflect the nature of their performances as they sit 10 points clear of the drop zone in 15th.
Graham Potter's side are synonymous with low-scoring affairs and they have established a similar pattern in the early stages of the FA Cup - scraping past Newport County on penalties before beating Blackpool 2-1 - and the Seagulls will now aspire to make the quarter-finals for the third time in four seasons.
The last time that Brighton overcame Leicester was back in the 2013-14 Championship campaign, and the Foxes eased to a 3-0 victory when the two sides met in the Premier League back in December.
Leicester City FA Cup form: WW
Leicester City form (all competitions): WWDLWD
Brighton & Hove Albion FA Cup form: WW
Brighton & Hove Albion form (all competitions): WWDWWD
Vardy was given a 30-minute run-out against Wolves at the weekend, but with Liverpool lying in wait for the Foxes on February 13, it would be a surprise to see the 34-year-old risked in this game.
Multiple changes from the Wolves stalemate could start with Danny Ward replacing Kasper Schmeichel in goal, while Nampalys Mendy, Marc Albrighton and Luke Thomas will all be hopeful of featuring from the first whistle.
Brighton defender Adam Webster was taken off with an ankle injury against Burnley, and Potter has conceded that he will not recover in time for this one.
Steele's absence should see Christian Walton handed an opportunity in between the sticks, while Adam Lallana, Danny Welbeck and Steven Alzate - the latter of whom was dropped for the Burnley trip after his winner at Anfield - may all earn starts too.
Leicester City possible starting lineup:
Ward; Pereira, Evans, Soyuncu, Thomas; Tielemans, Mendy; Albrighton, Maddison, Barnes; Iheanacho
Brighton & Hove Albion possible starting lineup:
Walton; White, Dunk, Burn; Veltman, Alzate, Bissouma, Karbownik; Lallana, Trossard; Welbeck
We say: Leicester City 1-0 Brighton & Hove Albion
Leicester have not exactly demonstrated a prolific nature with Vardy out of the team, and a raft of changes could have Brighton believing that a shock could be on the cards. The Seagulls have already beaten Liverpool away in 2021 and have found their defensive resolve, but we still think the Foxes will do enough to get over the line and keep their chances of a first ever FA Cup triumph alive.