The former England boss was appointed at the Championship outfit this week following the dismissal of Nigel Clough, but had to watch from the stands as Derby managed to come from behind and salvage a 4-4 draw against Ipswich Town.
Before McClaren's arrival, Derby lost two and drew two in their last four encounters in the league, leaving them 14th in the table.
The Rams have had trouble keeping goals out of their own net having just recorded one clean sheet so far this season, while Leeds sit just two points above them in the table following two wins in their last six matches.
Derby County: LWDLLD
Leeds United: LWLLLW
Possible starting lineups
Derby County: Grant; Smith, Buxton, Keogh, Forsyth, Davies; Bryson, Hughes, Ward, Sammon; Martin
Leeds United: Kenny; Peltier, Pearce, Lees, Warnock; Green, Austin, Mowatt, Tonge; McCormack, Hunt
Sports Mole says: 1-1