Juventus vs. Napoli (Wednesday, 5.45pm)
The Old Lady have picked up four points from their first two league games of the 2020-21 season, while Napoli have collected six from an available six, impressing in wins over Parma and Genoa.
We say: Juventus 1-1 Napoli
Juve will be determined to return to winning ways in Italy's top flight, but the champions are in for a tough examination this weekend. Napoli have been excellent in their first two matches, and we expect Gattuso's side to pick up a point from their trip to the Allianz Stadium on Sunday night.
Inter Milan vs. Sassuolo (Wednesday, 5.45pm)
As they continue their relentless Scudetto hunt against the exciting Emilian side, Antonio Conte's men could go 11 points clear at the top with a win, as they fulfill a fixture postponed just before the international break.
We say: Inter Milan 1-1 Sassuolo
Inter have been grinding out a series of positive results in recent weeks, with the emphasis firmly on substance over style since their explosive victory in February's decisive Milan Derby.
Even though Sassuolo are still without some integral parts of their attacking machinery, recent goalscoring exploits mean they can hope to pull off another upset to add to a long litany they have accumulated over recent years.
Even if Inter's winning run could be finally brought to an end by free-wheeling opponents, free of pressure and intent on attack, a point would suffice to keep the chasing pack at arm's length heading into the final stretch.