The Italian champions have won nine and drawn one of their 10 league matches this season to top the division, and they will fancy their chances of overcoming a Cagliari side that currently occupies 12th spot in the table.
Juventus have not lost a league match in front of their own supporters since April, although Genoa held them to a 1-1 draw in Turin on October 20.
Here, Sports Mole takes a look at how Juventus could line up in Saturday night's affair.
Giorgio Chiellini was forced to withdraw from the starting XI ahead of the clash with Empoli last weekend, and the experienced centre-back is a doubt for Saturday's clash with Cagliari.
As a result, Daniele Rugani should continue in central defence alongside Leonardo Bonucci. Emre Can and Sami Khedira are also both out, meaning that Blaise Matuidi should keep his position in the middle of the park.
Mario Mandzukic played for the club's Under-23 side earlier this week as he stepped up his recovery from an ankle problem, but this match will surely come too soon for the 2018 World Cup finalist.