La Roja met the Azzurri in the final of the European Championships last summer with the former winning 4-0, and the Real Madrid centre-back feels that the Italians will approach Thursday's game in largely the same manner.
"I think Italy will have the same philosophy as a year ago," Ramos told reporters.
"We do not expect any surprises. We know perfectly well how Italy play and we know that a very complicated game awaits us.
"[Italy] have a mixture of young players and veterans who will make life more difficult for us than in the Euro 2012 Final. We cannot relax."
Spain won all three of their group games en route to the semis, while Italy overcame Mexico and Japan before they were beaten 4-2 by Brazil on Saturday.