Murphy joined the club on loan from Celtic and will begin his third spell at Portman Road by offering support to Michael Chopra in attack.
Taylor also makes his first start for Jewell's side after leaving Peterborough United, but George Boyd's proposed transfer could not be completed.
However, the on-loan Wolves winger starts on the bench, with James Vaughan being given his first start for the Terriers.
Ipswich Town: Loach, Ainsley, Chambers, Smith, Cresswell, Taylor, Luongo, Drury, Martin, Murphy, Chopra
Huddersfield Town: Smithies, Dixon, Lynch, Clarke, Hunt, Southern, Norwood, Clayton, Ward, Vaughan, Novak