Perhaps nobody should be surprised that Conte, who guided Chelsea to a Premier League title during his first season in charge, is threatening to do something similar at Inter.
Following a number of years in the wilderness after Jose Mourinho's reign, with Inter appointing 13 different managers since the Portuguese's departure in 2010, Conte has instilled some genuine pedigree and stability into this side.
That they have only failed to win two of their 14 Serie A outings this term is a testament to the remarkably solid foundation on which this team is built.
However, despite the common perception of Conte as a conservative manager, Inter's performances this season have been largely hallmarked by building from the back, working the ball quickly through midfield lines and into the lethal pairing of Romelu Lukaku and Lautaro Martinez.
Most teams, like Napoli in 2018, who get close to Juventus tend to fall away, unable to sustain the same level over nine months, but this Inter team under Conte feels different.
Although not on the same scale as Inter, Roma can also claim to be enjoying the start made under Fonseca, appointed over the summer following a disappointing 2019-20 campaign during which they finished sixth in the table.
Sitting just two points behind third-placed Lazio, Roma's performances in Serie A this term have been, above all, exciting to watch, with the side picking up four red cards since the end of September.
At the back, Manchester United loanee Chris Smalling, deemed surplus to requirements by the under-pressure Ole Gunnar Solskjaer, has been one of the club's star performers, adding to the feeling that this is a side built on new and improved faces.
Victory at San Siro, however, would certainly serve as the biggest achievement of Fonseca's reign so far as Roma aim to consolidate their position in the Champions League places.
Recent Inter Milan form: WLWWWW
Recent Roma form: WLLWWW
Roma's injury list is notably more severe: Pastore is a major doubt due to a hip problem and Kluivert is definitely out following a recent thigh injury.
Inter Milan possible starting lineup:
Handanovic; D'Ambrosio, De Vrij, Skriniar; Candreva, Vecino, Brozovic, Valero, Lazaro, Martinez, Lukaku
Roma possible starting lineup:
Lopez; Santon, Mancini, Smalling, Kolarov; Veretout, Diawara; Mkhitaryan, Pellegrini, Under; Dzeko
We say: Inter Milan 2-0 Roma
Inter feel imperious at this moment in time, playing with a system that is affording them greater control and precision, under a manager whose ruthless winning mentality is clearly transmitting to his squad. Roma look set to put up a good fight but, in the face of Inter's muscle, will ultimately come up short.